Capsule Inclox 250 - mg
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About the Product
Full Description
Presentation
\nInclox 250 : Each capsule contains Flucloxacillin 250 mg as Flucloxacillin Sodium BP.
\nInclox 500 : Each capsule contains Flucloxacillin 500 mg as Flucloxacillin Sodium BP.
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\nDescription
\nFlucloxacillin is a narrow-spectrum antibiotic with considerable activity against the following common Gram-positive organisms:
\nPenicillinase producing Staphylococcus aureus
\nPenicillinase sensitive Staphylococcus aureus
\n?-haemolytic streptococci (Streptococcus pyogenes)
\nStreptococcus pneumoniae
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\nIt has little activity against Gram-negative bacilli. However, the Gram-negative organisms Neisseria gonorrhoeae and Neisseria meningitidis come within the range of activity. Flucloxacillin kills bacteria by inhibiting the formation of cell wall of bacteria
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\nIndications
\nSkin and Soft Tissue Infections: Boils, abscesses, carbuncles, furunculosis,infected wounds, infected burns, protection of skin grafts, otitis media and externa, impetigo.
\nInfected Skin Conditions. Ulcer, eczema and acne.
\nRespiratory Tract Infections: Pneumonia, lung abscess, empyema, sinusitis,pharyngitis, tonsillitis, quinsy.
\nOther infections caused by Flucloxacillin-sensitive organisms such as osteomyelitis, enteritis, endocarditis, urinary tract infection, meningitis, septicaemia.
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\nFlucloxacillin is also indicated for use as a prophylactic agent during major surgical procedures where appropriate, for example, cardiothoracic and orthopaedic surgery
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\nDosage & Administration
\nAdults (including elderly patients):
\nOral:
\n250-500mg three to four times a day. Oral doses should be administered 1 hour before meal
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\nChildren
\n2-10 years: Half of adult dose
\nUnder 2 years: One fourth of adult dose
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\nChildren have been given doses of 12.5mg/kg body weight four times a day.
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\nPatients with impaired renal function:
\nAs common with other penicillins, Flucloxacillin usage in patients with renal impairment does not usually require dosage reduction. However in the presence of severe renal failure (creatinine clearance<10 ml/min) a reduction in dose or an extension of dose interval should be considered.
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\nDirections for reconstitution
\nInclox dry powder for syrup :
\nAdd 60 ml (with the help of supplied measuring cup) of boiled and cooled water to the dry mixture in the bottle. For ease of preparation add water to the bottle in two portions. Shake the bottle well after each addition of water until all the powder is in syrup.
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\nNote:
\nShake the bottle well before each use.
\nKeep the bottle tightly closed.
\nSide Effects
\nThere have been some common side effects of GIT such as nausea, vomiting, diarrhoea, dyspepsia and other minor gastrointestinal disturbances. Besides these rashes, urticaria, purpura, fever, interstitial nephritis, hepatitis and cholestatic jaundice have been reported
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\nPrecautions
\nN/A
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\nUse in Pregnancy & Lactation
\nUse in pregnancy
\nPenicillins are generally considered safe for use in pregnancy. Animal studies with Flucloxacillin have shown no teratogenic effects.
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\nUse in lactation
\nFlucloxacillin is excreted in breast milk in trace amounts. Flucloxacillin may be administered during the period of lactation
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\nOver Dose
\nAlthough overdosage problems are unlikely to occur with penicillins, and should be treated symptomatically
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\nCommercial Pack
\nInclox 250 : Each box contains 5 strips of 10 capsules.
\nInclox 500 : Each box contains 5 strips of 10 capsules.
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