Capsule Lincocin 300 mg
৳ 15
Order By Call:
+88 01540 384 786 (Mobile)
+88 01819 479 004 (WhatsApp)
Payment Methods
About the Product
Full Description
LINCOCIN \n(Clindamycin Hydrochloride BP) Capsule \n \nDESCRIPTION \nClindamycin is a lincosamide antibiotic used in the treatment of infections caused by susceptible microorganisms. It is a semisynthetic antibiotic produced from lincomycin. Clindamycin is rapidly absorbed after oral administration. Concomitant administration of food does not appreciably modify the serum concentrations. Serum level studies following multiple doses of Clindamycin for up to 14 days show no evidence of accumulation or altered metabolism of drug. Clindamycin is widely distributed in body fluids and tissues (including bones). The average biological half-life is 2.4 hours. No significant levels of Clindamycin are attained in the cerebrospinal fluid (even in the presence of inflamed meninges). Clindamycin is bacteriostatic. It inhibits bacterial protein synthesis by binding to the 50S subunit of the ribosome. It has activity against Aerobic gram-positive cocci, including: Staphylococcus aureus, Staphylococcus epidermidis (penicillinase and non-penicillinase producing strains), Streptococci, Pneumococci. Anaerobic gramnegative bacilli, including: Bacteroides species, Fusobacterium pecies. Anaerobic gram-positive non-spore forming bacilli including: Propionibacterium species, Eubacterium species, Actinomyces species. Anaerobic and microaerophilic gram-positive cocci, including: Peptococcus species, Peptostreptococcus species, Microaerophilic streptococci, C. perferinges, B. fragilis. \n \nCOMPOSITION \nLINCOCIN 150: Each capsule contains Clindamycin Hydrochloride BP equivalent to Clindamycin 150 mg. \nLINCOCIN 300: Each capsule contains Clindamycin Hydrochloride BP equivalent to Clindamycin 300 mg. \n \nINDICATIONS \n? Serious Respiratory tract infections including bronchitis, emphysema, pneumonia and lung abscess. \n? Serious skin and soft tissue infection including Acne \n? Bone and bone joint infections including osteomyelitis and septic arthritis. \n? Intra-abdominal infections such as peritonitis intra-abdominal abscess. \n? Infection of genital tract infection as endometritis, nongonococcol tuboovarian abscess, Pelvic Infections, pelvic cellulites and post surgical vaginal cuff infection. \n? Septicemia and endocarditis. \n? Dental infection such as periodontal abscess and periodontitis. \n? It is also used as alternative therapy for infection of penicillin-allergic patients caused by penicillin susceptible microorganisms. \n? As combination with Quinine sulfate for the treatment of uncomplicated chloroquine-resistant Plasmodium falciporum Malaria. \n? Clindamycin can also be used for infections associated with meticillin-resistant staphylococcus aureous (MRSA) in bronchiectasis, bone and bone joint infections and skin and soft tissue infections. \n \nDOSAGE AND ADMINISTRATION \n \nAdult: \nSerious infections: 150 to 300 mg every 6 hours. More severe infections: 300 to 450 mg every 6 hours. \n \nChildren: \nSerious infections: 8 to 16 mg/kg/day divided into three or four equal doses. More severe infections: 16 to 20 mg/kg/day divided into three or four equal doses. To avoid the possibility of esophageal irritation, LINCOCIN Capsules should be taken with a full glass of water. Or as directed by the physician. \n \nSIDE EFFECTS \nSide effects include diarrhoea (discontinue treatment), abdominal discomfort, Oesophagitis, Oesophageal ulcers, taste disturbances, nausea, vomiting, antibiotic-associated colitis, jaundice, rash, pruritis and urticaria. \n \nCONTRAINDICATIONS \nClindamycin is contraindicated in individuals with a history of hypersensitivity to preparations containing clindamycin. \n \nPRECAUTIONS \nDiscontinue immediately if diarrhoea or colitis develops. Monitor liver and renal function if treatment exceeds 10 days. Clindamycin occasionally results in overgrowth of nonsusceptible organismsparticularly yeast. Appropriate measures should be taken if super infections occur. \n \nUSE IN CHILDREN \nWhen Clindamycin is administered to the pediatric population (birth to 16 years), appropriate monitoring of organ system functions is desirable. \n \nUSE IN PREGNANCY AND LACTATION \nPregnancy category B. \nThe drug should be used in pregnancy only if clearly needed. \nClindamycin has been reported to appear in breast milk. So it is not \nrecommended for lactating mother if not clearly needed. \n \nUSE IN ELDERLY \nPatients should be carefully monitored for the development of diarrhea. \n \nDRUG INTERACTIONS \nAntagonism has been demonstrated between Clindamycin and Erythromycin in vitro. Because of possible clinical significance, these two drugs should not be administered concurrently. \n \nSUPPLY \nLINCOCIN 150: Each box contains 3X10 capsules in blister strips. \nLINCOCIN 300: Each box contains 3X10 capsules in blister strips. \nStore in a cool & dry place, protected from light. \nKeep all medicines out of reach of children. \n* Further information is available on request. \n \nFOR HEALTH, VIGOUR AND HAPPINESS
